What's the matter?

Kate: What's the matter? Why are you complaining?
Frank: Oh, I have a terrible headache!
Kate: Well, you should stop smoking!
Frank: It's not that.
Kate: Why don't you take an aspirin?
Frank: No, they don't have any effect.
Kate: Then, you'd better see a doctor.
Frank: Yes, maybe you're right.
Kate: If you want to see Dr Smith, you need to call him right now.
Frank: Do you think I should?